I’itikaf is a Sunnah. This means that if a person wants to leave after 5 minutes, this is up to him and there isn’t anything forcing him to stay.

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It is permissible for a woman to make I’itikaf if it is safe for her in the masjid.

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If you mean leaving the masjid you are doing itikaf in to another masjid, this is not permissible.

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